The interplay between gastrointestinal (GI) health and psychological functioning has emerged as a pivotal area of research in contemporary biomedical and psychological studies. This bidirectional communication, commonly referred to as the gut–brain axis, involves complex interactions between the central nervous system (CNS) and the enteric nervous system (ENS), mediated through neural, hormonal, and immunological pathways. Disturbances in gastrointestinal function and alterations in microbial composition have been increasingly associated with stress, anxiety, depression, and reduced emotional well-being. The gut’s role in neurotransmitter synthesis, immune modulation, and microbial balance highlights its significance in regulating mood and psychological resilience. This review synthesizes recent findings on the neurochemical, immunological, and psychosocial mechanisms underlying the gut–brain connection. Furthermore, it discusses the clinical implications of these discoveries, emphasizing integrative interventions such as dietary modification, probiotic supplementation, and psychotherapeutic strategies, including cognitive behavioral therapy (CBT). Advancing the understanding of gut–brain interactions provides a framework for novel approaches to enhancing emotional well-being by simultaneously targeting gastrointestinal and psychological health.

Authors:
Nino Rachvelishvili, Grigol Robakidze University, Georgia
Aisel Ajalieva-Akhverdova, Grigol Robaqidze Univeristy, Georgia

About the Presenter(s)
Dr. Nino Rachvelishvili is an Assistant Professor of Psychology at Grigol Robakidze University, Tbilisi, Georgia. Her Current Project: The Influence of Gastrointestinal Health on Emotional Well-Being.

See this presentation on the full schedule – Wednesday Schedule

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